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Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.

Autophosphorylation of Ca2+/calmodulin-dependent protein kinase II converts the enzyme to a Ca2+-independent form. The time course for this conversion correlates with the autophosphorylation of a threonine residue located within a thermolytic phosphopeptide common to the alpha and beta/beta' subunit...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Thiel, G, Czernik, A J, Gorelick, F, Nairn, A C, Greengard, P
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1988
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281965/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2842767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.17.6337
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