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Nuclear Reorganization of DNA Mismatch Repair Proteins in Response to DNA Damage

The DNA mismatch repair (MMR) system is highly conserved and vital for preserving genomic integrity. Current mechanistic models for MMR are mainly derived from in vitro assays including reconstitution of strand specific MMR and DNA binding assays using short oligonucleotides. However, fundamental qu...

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Detalhes bibliográficos
Main Authors: Mastrocola, Adam S., Heinen, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819642/
https://ncbi.nlm.nih.gov/pubmed/20004149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.11.003
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