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X-ray structures of NS1 effector domain mutants
The influenza A virus nonstructural protein NS1 is a multifunctional dimeric protein that acts as a potent inhibitor of the host cellular antiviral state. The C-terminal effector domain of NS1 binds host proteins, including CPSF30, and is a target for the development of new antiviral drugs. Here we...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819631/ https://ncbi.nlm.nih.gov/pubmed/19995550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.12.008 |
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