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X-ray structures of NS1 effector domain mutants

The influenza A virus nonstructural protein NS1 is a multifunctional dimeric protein that acts as a potent inhibitor of the host cellular antiviral state. The C-terminal effector domain of NS1 binds host proteins, including CPSF30, and is a target for the development of new antiviral drugs. Here we...

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Autors principals: Xia, Shuangluo, Robertus, Jon D.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819631/
https://ncbi.nlm.nih.gov/pubmed/19995550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.12.008
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