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Selective modulation of protein kinase isozymes by the site-selective analog 8-chloroadenosine 3',5'-cyclic monophosphate provides a biological means for control of human colon cancer cell growth.

Differential expression of type I and type II cAMP-dependent protein kinase isozymes has been linked to growth regulation and differentiation. We examined the expression of protein kinase isozymes in the LS 174T human colon cancer cell line during 8-chloroadenosine 3',5'-cyclic monophospha...

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Main Authors: Ally, S, Tortora, G, Clair, T, Grieco, D, Merlo, G, Katsaros, D, Ogreid, D, Døskeland, S O, Jahnsen, T, Cho-Chung, Y S
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC281961/
https://ncbi.nlm.nih.gov/pubmed/3413098
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