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Ex Vivo Transfer of the Hoxc-8-interacting Domain of Smad1 by a Tropism-Modified Adenoviral Vector Results in Efficient Bone Formation in a Rabbit Model of Spinal Fusion
STUDY DESIGN: Ex vivo gene transfer for spinal fusion. OBJECTIVE: This study aimed to evaluate ex vivo transfer of the nuclear-localized Hoxc-8interacting domain of Smad1 (termed Smad1C) to rabbit bone marrow stromal cells (BMSCs) by a tropism-modified human adenovirus serotype 5 (Ad5) vector as a n...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819464/ https://ncbi.nlm.nih.gov/pubmed/20084034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BSD.0b013e318193b693 |
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