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Focal Adhesion Kinase Acts Downstream of EphB Receptors to Maintain Mature Dendritic Spines by Regulating Cofilin Activity

Dendritic spines are the postsynaptic sites of most excitatory synapses in the brain and are highly enriched in polymerized F-actin, which drives the formation and maintenance of mature dendritic spines and synapses. We propose that suppressing the activity of the actin-severing protein cofilin play...

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Main Authors: Shi, Yang, Pontrello, Crystal G., DeFea, Kathryn A., Reichardt, Louis F., Ethell, Iryna M.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819391/
https://ncbi.nlm.nih.gov/pubmed/19553453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4681-08.2009
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