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Focal Adhesion Kinase Acts Downstream of EphB Receptors to Maintain Mature Dendritic Spines by Regulating Cofilin Activity

Dendritic spines are the postsynaptic sites of most excitatory synapses in the brain and are highly enriched in polymerized F-actin, which drives the formation and maintenance of mature dendritic spines and synapses. We propose that suppressing the activity of the actin-severing protein cofilin play...

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Detalhes bibliográficos
Main Authors: Shi, Yang, Pontrello, Crystal G., DeFea, Kathryn A., Reichardt, Louis F., Ethell, Iryna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819391/
https://ncbi.nlm.nih.gov/pubmed/19553453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4681-08.2009
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