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Chemoprevention of mouse intestinal tumorigenesis by the CDK inhibitor SNS-032
Despite advances in screening and treatment, colorectal cancer (CRC) remains the second leading cause of cancer-related death in the United States. Cyclin-dependent kinases (Cdks) are deregulated in CRC by silencing of the Cdk inhibitor p16(Ink4a) and other mechanisms. We tested whether the small mo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819381/ https://ncbi.nlm.nih.gov/pubmed/19723896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0053 |
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