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Role of NADPH Oxidase and Stat3 in Statin-Mediated Protection against Diabetic Retinopathy

PURPOSE: Inhibitors of 3-hydroxy-3-methylglutaryl CoA reductase (statins) reduce signs of diabetic retinopathy in diabetic patients and animals. Indirect clinical evidence supports the actions of statins in improving cardiovascular function, but the mechanisms of their protective actions in the reti...

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Main Authors: Al-Shabrawey, Mohamed, Bartoli, Manuela, El-Remessy, Azza B., Ma, Guochuan, Matragoon, Suraporn, Lemtalsi, Tahira, Caldwell, R. William, Caldwell, Ruth B.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819293/
https://ncbi.nlm.nih.gov/pubmed/18378570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-1754
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