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Larval midgut destruction in Drosophila: Not dependent on caspases but suppressed by the loss of autophagy

While most programmed cell death (PCD) in animal development is reliant upon the caspase-dependent apoptotic pathway and subsequent cleavage of caspase substrates, we found that PCD in Drosophila larval midgut occurs normally in the absence of the main components of the apoptotic machinery. However,...

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Autors principals: Denton, Donna, Shravage, Bhupendra, Simin, Rachel, Baehrecke, Eric H., Kumar, Sharad
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819273/
https://ncbi.nlm.nih.gov/pubmed/20009534
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