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Autophagy, not apoptosis, is essential for midgut cell death in Drosophila

Most developmentally programmed cell death in metazoans is mediated by caspases. During Drosophila metamorphosis obsolete tissues, including the midgut and salivary glands, are removed by programmed cell death [1]. The initiator caspase Dronc and its activator Ark are required for the death of saliv...

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Détails bibliographiques
Auteurs principaux: Denton, Donna, Shravage, Bhupendra, Simin, Rachel, Mills, Kathryn, Berry, Deborah L, Baehrecke, Eric H, Kumar, Sharad
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783269/
https://ncbi.nlm.nih.gov/pubmed/19818615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.08.042
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