Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli.

Epitopes for antibodies that inhibit factor VIII procoagulant protein were analyzed by deletion mapping of factor VIII protein fragments expressed in Escherichia coli. A human factor VIII cDNA clone was used to generate E. coli expression vectors encoding fragments containing the 80-kDa factor VIII...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Scandella, D, DeGraaf Mahoney, S, Mattingly, M, Roeder, D, Timmons, L, Fulcher, C A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1988
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281923/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2457907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6152
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