Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli.

Epitopes for antibodies that inhibit factor VIII procoagulant protein were analyzed by deletion mapping of factor VIII protein fragments expressed in Escherichia coli. A human factor VIII cDNA clone was used to generate E. coli expression vectors encoding fragments containing the 80-kDa factor VIII...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Scandella, D, DeGraaf Mahoney, S, Mattingly, M, Roeder, D, Timmons, L, Fulcher, C A
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1988
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281923/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2457907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6152
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