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Targeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain development

Obscurin is a giant structural and signaling protein that participates in the assembly and structural integrity of striated myofibrils. Previous work has examined the physical interactions between obscurin and other cytoskeletal elements but its in vivo role in cell signaling, including the function...

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Detalhes bibliográficos
Main Authors: Raeker, Maide Ö., Bieniek, Ashley N., Ryan, Alison S., Tsai, Huai-Jen, Zahn, Katelin M., Russell, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819229/
https://ncbi.nlm.nih.gov/pubmed/19931525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.11.018
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