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The ratio of cholesterol 5,6-secosterols formed from ozone and singlet oxygen offers insight into the oxidation of cholesterol in vivo

Ongoing efforts to unravel the origins of the cholesterol 5,6-secosterols (1a and 1b) in biological systems have revealed that the two known chemical routes to these oxysterols; ozonolysis of cholesterol (3) and Hock-cleavage of 5-α-hydroperoxycholesterol (4a), are distinguishable based upon the rat...

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Detalhes bibliográficos
Main Authors: Wentworth, Anita D., Song, Byeong-Doo, Nieva, Jorge, Shafton, Asher, Tripurenani, Sangeetha, Wentworth, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819220/
https://ncbi.nlm.nih.gov/pubmed/19462099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b821584g
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