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Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats

We have recently reported that the endogenous mGlu2/3 agonist N-acetylaspartylglutamate (NAAG) and the N-acetylated-α-linked-acidic dipepetidase (NAALADase, a NAAG degradation enzyme) inhibitor 2-PMPA significantly inhibit cocaine self-administration and cocaine-induced reinstatement of drug-seeking...

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Detalhes bibliográficos
Main Authors: Peng, Xiao-Qing, Li, Jie, Gardner, Eliot L., Ashby, Charles R., Xi, Zheng-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819210/
https://ncbi.nlm.nih.gov/pubmed/19887067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.10.062
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