Inhibition of N-acetylated-alpha-Linked-Acidic Dipeptidase (NAALADase) by 2-PMPA Attenuates Cocaine-Induced Relapse in Rats: A NAAG-mGluR2/3-Mediated Mechanism

Pharmacological activation of group II metabotropic glutamate receptors (mGluR2/3) inhibits cocaine self-administration and reinstatement of drug-seeking behavior, suggesting a possible use of mGluR2/3 agonists in the treatment of cocaine dependence. In the present study, we investigated whether ele...

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Autores principales: Xi, Zheng-Xiong, Li, Xia, Peng, Xiao-Qing, Li, Jie, Chun, Lauren, Gardner, Eliot L., Thomas, Ajit G., Slusher, Barbara S., Ashby, Charles R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809121/
https://ncbi.nlm.nih.gov/pubmed/19895667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06478.x
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