Imaging biomarkers to predict response to anti-HER2 (ErbB2) therapy in preclinical models of breast cancer

PURPOSE: To evaluate non-invasive imaging methods as predictive biomarkers of response to trastuzumab in mouse models of HER2-overexpressing breast cancer. The correlation between tumor regression and molecular imaging of apoptosis, glucose metabolism, and cellular proliferation was evaluated longit...

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Bibliografiske detaljer
Main Authors: Shah, Chirayu, Miller, Todd W., Wyatt, Shelby K., McKinley, Eliot T., Olivares, Maria Graciela, Sanchez, Violeta, Nolting, Donald D., Buck, Jason R., Zhao, Ping, Ansari, M. Sib, Baldwin, Ronald M., Gore, John C., Schiff, Rachel, Arteaga, Carlos L., Manning, H. Charles
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819132/
https://ncbi.nlm.nih.gov/pubmed/19584166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2635
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