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A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent
Chalcones represent a class of natural products that inhibits tubulin assembly. In this study we designed and synthesized boronic acid analogs of chalcones in an effort to compare biological activities with combretastatin A-4, a potent inhibitor of tubulin polymerization. Systematic evaluation of th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819108/ https://ncbi.nlm.nih.gov/pubmed/20006519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.11.003 |
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