Homocysteine causes cerebrovascular leakage in mice

Elevated plasma homocysteine (Hcy) is associated with cerebrovascular disease and activates matrix metalloproteinases (MMPs), which lead to vascular remodeling that could disrupt the blood-brain barrier. To determine whether Hcy administration can increase brain microvascular leakage secondary to ac...

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Bibliographic Details
Main Authors: Lominadze, David, Roberts, Andrew M., Tyagi, Neetu, Moshal, Karni S., Tyagi, Suresh C.
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819019/
https://ncbi.nlm.nih.gov/pubmed/16258031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00376.2005
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