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Identification of DNA Methyltransferase 3a as a T cell Receptor-induced regulator of Th1 and Th2 differentiation

Antigen-specific T cell cytokine expression is dictated by the context in which T cell receptor (TCR) engagement occurs. Recently it has become clear that epigenetic changes play a role in this process. DNA Methyltransferase-3a (DNMT3a) is a de novo methyltransferase important to the epigenetic cont...

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Detalhes bibliográficos
Main Authors: Gamper, Christopher J., Agoston, Agoston T., Nelson, William G., Powell, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818975/
https://ncbi.nlm.nih.gov/pubmed/19625655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802960
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