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Template-dependent 3(′)–5(′) nucleotide addition is a shared feature of tRNA(His) guanylyltransferase enzymes from multiple domains of life
The presence of an additional 5(′) guanosine residue (G(-1)) is a unique feature of tRNA(His). G(-1) is incorporated posttranscriptionally in eukarya via an unusual 3(′)–5(′) nucleotide addition reaction catalyzed by the tRNA(His) guanylyltransferase (Thg1). Yeast Thg1 catalyzes an unexpected second...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818966/ https://ncbi.nlm.nih.gov/pubmed/20080734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910961107 |
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