載入...

Affinity-based Selection of Regulatory T Cells Occurs Independent of Agonist-mediated Induction of Foxp3 Expression

Natural regulatory T (nT(reg)) cells recognize self-peptides with high affinity, yet the understanding of how affinity influences their selection in the thymus is incomplete. We use altered peptide ligands in transgenic mice and in organ culture to create thymic environments spanning a broad range o...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Relland, Lance M., Mishra, Manoj K., Haribhai, Dipica, Edwards, Brandon, Ziegelbauer, Jennifer, Williams, Calvin B.
格式: Artigo
語言:Inglês
出版: 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818884/
https://ncbi.nlm.nih.gov/pubmed/19155480
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!