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An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.

We have identified a protein present only in erythroid cells that binds to two adjacent sites within an enhancer region of the chicken beta-globin locus. Mutation of the sites, so that binding by the factor can no longer be detected in vitro, leads to a loss of enhancing ability, assayed by transien...

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Detalles Bibliográficos
Main Authors: Evans, T, Reitman, M, Felsenfeld, G
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC281888/
https://ncbi.nlm.nih.gov/pubmed/3413070
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