Transcription-dependent cytosine deamination: a novel mechanism in ultraviolet light-induced mutagenesis

Skin cancer is the most ubiquitous cancer type in the Caucasian population and its incidence is increasing rapidly [1]. Transcribed, proliferation-related, genes in dermal stem cells are targets for the induction of ultraviolet light (UV)-induced mutations that drive carcinogenesis. We have recently...

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Hlavní autoři: Hendriks, Giel, Calléja, Fabienne, Besaratinia, Ahmad, Vrieling, Harry, Pfeifer, Gerd P., Mullenders, Leon H.F., Jansen, Jacob G., de Wind, Niels
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818831/
https://ncbi.nlm.nih.gov/pubmed/20045328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.11.061
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