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Transcription-coupled repair and apoptosis provide specific protection against transcription-associated mutagenesis by ultraviolet light
Recent data reveal that gene transcription affects genome stability in mammalian cells. For example, transcription of DNA that is damaged by the most prevalent exogenous genotoxin, UV light, induces nucleotide substitutions and chromosomal instability, collectively called UV-induced transcription-as...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023636/ https://ncbi.nlm.nih.gov/pubmed/21326899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.1.2.12788 |
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