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L-4F Alters Hyperlipidemic (but not Normal) Mouse Plasma to Reduce Platelet Aggregation
OBJECTIVE: Hyperlipidemia is associated with platelet hyper-reactivity. We hypothesized that L-4F, an apoA-I mimetic peptide, would inhibit platelet aggregation in hyperlipidemic mice. METHODS AND RESULTS: Injecting L-4F into apoE null and LDL receptor null mice resulted in a significant reduction i...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818809/ https://ncbi.nlm.nih.gov/pubmed/19965777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.200162 |
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