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Tobacco smoke promotes lung tumorigenesis by triggering IKKβ and JNK1 dependent inflammation
Chronic exposure to tobacco smoke, which contains over 60 tumor-initiating carcinogens, is the major risk factor for development of lung cancer, accounting for a large portion of cancer-related deaths worldwide. It is well established that tobacco smoke is a tumor initiator, but we asked whether it...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818776/ https://ncbi.nlm.nih.gov/pubmed/20129250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.12.008 |
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