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Tobacco smoke promotes lung tumorigenesis by triggering IKKβ and JNK1 dependent inflammation

Chronic exposure to tobacco smoke, which contains over 60 tumor-initiating carcinogens, is the major risk factor for development of lung cancer, accounting for a large portion of cancer-related deaths worldwide. It is well established that tobacco smoke is a tumor initiator, but we asked whether it...

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Detalhes bibliográficos
Main Authors: Takahashi, Hiroyuki, Ogata, Hisanobu, Nishigaki, Reiko, Broide, David H., Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818776/
https://ncbi.nlm.nih.gov/pubmed/20129250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.12.008
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