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Conformational Changes in the Nicotinic Acetylcholine Receptor During Gating and Desensitization

The nicotinic acetylcholine receptor (nAChR) is a member of the important Cys-loop ligand-gated ion channel superfamily that modulates neuronal excitability. After responding to their agonists, their actions are terminated either by removal of ligand or by fast and slow desensitization, processes th...

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Detalhes bibliográficos
Main Authors: Yamodo, Innocent H., Chiara, David C., Cohen, Jonathan B., Miller, Keith W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818735/
https://ncbi.nlm.nih.gov/pubmed/19961216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901550p
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