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Systemic candesartan reduces brain angiotensin II via downregulation of brain renin–angiotensin system

The renin–angiotensin system has an important function in the regulation of blood pressure as well as in pathophysiological processes in the central nervous system. We examined the effects of the angiotensin receptor blocker candesartan (10 mg kg(−1) per day, p.o.) on brain angiotensin II levels in...

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Bibliographische Detailangaben
Hauptverfasser: Pelisch, Nicolas, Hosomi, Naohisa, Ueno, Masaki, Masugata, Hisashi, Murao, Koji, Hitomi, Hirofumi, Nakano, Daisuke, Kobori, Hiroyuki, Nishiyama, Akira, Kohno, Masakazu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818705/
https://ncbi.nlm.nih.gov/pubmed/19942928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2009.200
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