Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes

PURPOSE: Hepatocellular cancer (HCC) is highly resistant to chemotherapy and is associated with a poor prognosis. Chronic hepatitis C (HCV) infection is a major cause of HCC. However, the effect of viral proteins in mediating chemosensitivity in tumor cells is unknown. We postulated that HCV viral p...

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Détails bibliographiques
Auteurs principaux: Braconi, Chiara, Valeri, Nicola, Gasparini, Pierluigi, Huang, Nianyuan, Taccioli, Cristian, Nuovo, Gerard, Suzuki, Tetsuro, Croce, Carlo Maria, Patel, Tushar
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818698/
https://ncbi.nlm.nih.gov/pubmed/20103677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2123
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