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AGGRESSIVE CHRONIC LYMPHOCYTIC LEUKEMIA WITH ELEVATED GENOMIC COMPLEXITY IS ASSOCIATED WITH MULTIPLE GENE DEFECTS IN THE RESPONSE TO DNA-DOUBLE STRAND BREAKS
PURPOSE: Genomic complexity is present in ~15–30% of all CLL and has emerged as a strong independent predictor of rapid disease progression and short remission duration in CLL. We conducted this study to advance our understanding of the causes of genomic complexity in CLL. EXPERIMENTAL DESIGN: We ha...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818663/ https://ncbi.nlm.nih.gov/pubmed/20086003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2534 |
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