Elevated endogenous expression of the dominant negative basic helix-loop-helix protein ID1 correlates with significant centrosome abnormalities in human tumor cells

BACKGROUND: ID proteins are dominant negative inhibitors of basic helix-loop-helix transcription factors that have multiple functions during development and cellular differentiation. Ectopic (over-)expression of ID1 extends the lifespan of primary human epithelial cells. High expression levels of ID...

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Bibliographic Details
Main Authors: Manthey, Carolin, Mern, Demissew S, Gutmann, Anja, Zielinski, Anne J, Herz, Corinna, Lassmann, Silke, Hasskarl, Jens
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818612/
https://ncbi.nlm.nih.gov/pubmed/20070914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-11-2
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