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Synthesis and application of a photoaffinity analog of dehydroepiandrosterone (DHEA)
We have synthesized an analog of dehydroepiandrosterone (DHEA, 1) containing both a benzophenone (BP) and a biotin (Bt) group (DHEA-BP-Bt, 8). Compound 8 was prepared by functionalization on C-17 of 1. Biocytin was reacted with 4-benzoylbenzoic acid and the product was condensed with 1 containing a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818606/ https://ncbi.nlm.nih.gov/pubmed/20031404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.12.019 |
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