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Activation of the WAVE complex by coincident signals controls actin assembly

WAVE proteins link upstream signals to actin nucleation by activating the Arp2/3 complex and are at the core of regulatory pathways driving membrane protrusion. They are found in heteropentameric complexes whose role in regulating WAVE function is presently unclear. Here we demonstrate that purified...

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Detalhes bibliográficos
Main Authors: Lebensohn, Andres M., Kirschner, Marc W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818508/
https://ncbi.nlm.nih.gov/pubmed/19917258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.10.024
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