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A Convergent Stereoselective Synthesis of Quinolizidines and Indolizidines: Chemoselective Coupling of 2-Hydroxymethyl Substituted Allylic Silanes with Imines

[Image: see text] A convergent synthesis of stereodefined indolizidines and quinolizidines is described through chemoselective allyltransfer between 2-hydroxymethyl substituted allylic silanes and imines. Overall, highly substituted heterocycles that contain three stereogenic centers and up to four...

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Detalhes bibliográficos
Main Authors: Yang, Dexi, Micalizio, Glenn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818501/
https://ncbi.nlm.nih.gov/pubmed/19950989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908504z
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