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p21ras-induced responsiveness of phosphatidylinositol turnover to bradykinin is a receptor number effect.
Proteins encoded by ras genes have recently been reported to couple certain growth factor receptors to phospholipase C, the enzyme catalyzing phosphatidylinositol breakdown. To investigate this hypothesis, the normal and the transforming Ha-, Ki-, and N-ras genes were each transfected into Rat-1 fib...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281847/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2901087/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.5774 |
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