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Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1.

V79 Chinese hamster fibroblasts are widely used for mutagenicity testing but have the serious limitation that they do not express cytochromes P-450, which are needed for the activation of many promutagens to mutagenic metabolites. A full-length cDNA clone encoding the monooxygenase cytochrome P-450I...

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Bibliografski detalji
Glavni autori: Doehmer, J, Dogra, S, Friedberg, T, Monier, S, Adesnik, M, Glatt, H, Oesch, F
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC281846/
https://ncbi.nlm.nih.gov/pubmed/3137560
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