Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1.

V79 Chinese hamster fibroblasts are widely used for mutagenicity testing but have the serious limitation that they do not express cytochromes P-450, which are needed for the activation of many promutagens to mutagenic metabolites. A full-length cDNA clone encoding the monooxygenase cytochrome P-450I...

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Bibliografiske detaljer
Main Authors: Doehmer, J, Dogra, S, Friedberg, T, Monier, S, Adesnik, M, Glatt, H, Oesch, F
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC281846/
https://ncbi.nlm.nih.gov/pubmed/3137560
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