Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast

In Saccharomyces cerevisiae and Candida albicans, two enzymes of the ergosterol biosynthetic pathway, oxidosqualene cyclase (Erg7p) and 3-keto reductase (Erg27p) interact such that loss of the 3-keto reductase also results in a concomitant loss of activity of the upstream oxidosqualene cyclase. This...

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Main Authors: Taramino, S., Valachovic, M., Oliaro-Bosso, S., Viola, F., Teske, B., Bard, M., Balliano, G.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818386/
https://ncbi.nlm.nih.gov/pubmed/19879375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.10.005
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