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The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia.
Inactivation of normally expressed genes may play a role in the formation and/or progression of human cancers. Methylation of cytosine in DNA could potentially participate in such alterations of gene expression. Abnormalities in DNA methylation are a consistent feature of human neoplasms, and we now...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2840671/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5693 |
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