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The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia.

Inactivation of normally expressed genes may play a role in the formation and/or progression of human cancers. Methylation of cytosine in DNA could potentially participate in such alterations of gene expression. Abnormalities in DNA methylation are a consistent feature of human neoplasms, and we now...

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Detalhes bibliográficos
Main Authors: de Bustros, A, Nelkin, B D, Silverman, A, Ehrlich, G, Poiesz, B, Baylin, S B
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC281826/
https://ncbi.nlm.nih.gov/pubmed/2840671
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