RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells

An important function of the RNAase-III enzyme Dicer is to process microRNA precursors into ~22-nucleotide non-coding small RNAs. But little is known about the role of Dicer in mammalian brain formation and neural stem cell (NSC) development. Here we show that Dicer plays a crucial role in controlli...

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Detalhes bibliográficos
Main Authors: Kawase-Koga, Yoko, Low, Roger, Otaegi, Gaizka, Pollock, Andrew, Deng, Haiteng, Eisenhaber, Frank, Maurer-Stroh, Sebastian, Sun, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818196/
https://ncbi.nlm.nih.gov/pubmed/20103535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.059659
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