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Inhibitors of glycoprotein processing alter T-cell proliferative responses to antigen and to interleukin 2.

Most of the cell-surface molecules involved in T-cell immune responses are N-linked glycoproteins. We have investigated the effects of inhibitors of glycoprotein processing on specific T-cell functions, with the dual aims of examining the functional role of carbohydrate and of testing the usefulness...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Wall, K A, Pierce, J D, Elbein, A D
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281816/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3135550/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5644
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