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The T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated Ia.

The membrane protein CD4 is commonly found on mature T cells specific for antigen in association with class II major histocompatibility complex (MHC; Ia) proteins. This correlation has led to the suggestion that CD4 binds to a monomorphic region of the Ia molecule on the antigen-presenting cell (APC...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gay, D, Buus, S, Pasternak, J, Kappler, J, Marrack, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281813/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3261012/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5629
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