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Absence of methylation of a CpG-rich region at the 5' end of the MIC2 gene on the active X, the inactive X, and the Y chromosome.

We have identified and characterized a Hpa II tiny fragment (HTF) island associated with the promoter region of the pseudoautosomal gene MIC2. The MIC2 HTF island is unmethylated on both the active and inactive X chromosome and is similarly unmethylated on the Y chromosome. Unlike the majority of ge...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Goodfellow, P J, Mondello, C, Darling, S M, Pym, B, Little, P, Goodfellow, P N
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281808/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2456574/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5605
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