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The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

DNA methylation is an important regulator of genetic information in species ranging from bacteria to humans. DNA methylation appears to be critical for mammalian development because mice nullizygous for a targeted disruption of the DNMT1 DNA methyltransferase die at an early embryonic stage. No DNA...

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Publicado en:Proc Natl Acad Sci U S A
Principais autores: Hansen, R. Scott, Wijmenga, Cisca, Luo, Ping, Stanek, Ann M., Canfield, Theresa K., Weemaes, Corry M. R., Gartler, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14412
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