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The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

DNA methylation is an important regulator of genetic information in species ranging from bacteria to humans. DNA methylation appears to be critical for mammalian development because mice nullizygous for a targeted disruption of the DNMT1 DNA methyltransferase die at an early embryonic stage. No DNA...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hansen, R. Scott, Wijmenga, Cisca, Luo, Ping, Stanek, Ann M., Canfield, Theresa K., Weemaes, Corry M. R., Gartler, Stanley M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14412
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