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Sequence periodicity and secondary structure propensity in model proteins

We explore the question of whether local effects (originating from the amino acids intrinsic secondary structure propensities) or nonlocal effects (reflecting the sequence of amino acids as a whole) play a larger role in determining the fold of globular proteins. Earlier circular dichroism studies h...

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Detalhes bibliográficos
Main Authors: Bellesia, Giovanni, Jewett, Andrew Iain, Shea, Joan-Emma
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817849/
https://ncbi.nlm.nih.gov/pubmed/19937649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.288
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