ENU Mutagenesis Reveals a Novel Phenotype of Reduced Limb Strength in Mice Lacking Fibrillin 2

BACKGROUND: Fibrillins 1 (FBN1) and 2 (FBN2) are components of microfibrils, microfilaments that are present in many connective tissues, either alone or in association with elastin. Marfan's syndrome and congenital contractural arachnodactyly (CCA) result from dominant mutations in the genes FB...

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Detalhes bibliográficos
Main Authors: Miller, Gaynor, Neilan, Monica, Chia, Ruth, Gheryani, Nabeia, Holt, Natalie, Charbit, Annabelle, Wells, Sara, Tucci, Valter, Lalanne, Zuzanne, Denny, Paul, Fisher, Elizabeth M. C., Cheeseman, Michael, Askew, Graham N., Dear, T. Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817753/
https://ncbi.nlm.nih.gov/pubmed/20161761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009137
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